- Hank Williams and John Mellencamp were born with a birth defect known as spina bifida.
- Demi Moore was born with crossed eyes, an affliction corrected in her youth thanks to two surgical procedures.
- Cher struggled with dyslexia for many years, and used to have friends read scripts to her so that she could memorize them.
- Tom Cruise has a fused midline incisor, meaning that instead of the normal four front teeth in his upper jaw, he only has three.
- President Grover Cleveland had a tumor removed from the roof of his mouth while “”resting”” on board a yacht in Long Island Sound.
- Dolly Parton’s wig makes her appear notably taller than the balding Danny Devito.